In a sense, we understand why they happen, but we don’t have a good way to predict them yet,” says Ming Dao, a principal research scientist in MIT’s Department of Materials Science and Engineering and one of the senior authors of the study. “These painful crises are very much unpredictable. The findings also represent a step toward being able to predict when such a crisis might occur. Treatments may include a phlebotomy (withdrawing blood to decrease the volume), a low-dose aspirin regimen, or medications to decrease blood cells.One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain and swelling in the affected body parts.Ī new study from MIT sheds light on how these events, known as vaso-occlusive pain crises, arise. Treatment for erythrocytosis will vary according to the severity or progression of the disorder. It is a slow growing type of blood cancer, but if left untreated, it can result in a more serious type of cancer such as leukemia. Polycythemia vera is a genetically acquired blood cancer in which your body makes too many blood cells. Symptoms of erythrocystosis include:Įrythrocytosis can sometimes lead to other more serious conditions such as polycythemia vera. Non-familial erythrocystosis can be caused from long term exposure to high altitude, chronic lung or heart disease, sleep apnea, chronic smoking, or certain types of tumors. Familial erythrocytosis is where a person inherits the disorder, and non-familial erythrocytosis is where a person acquires the disease later in life. While the prevalence of erythrocytosis is unknown, researchers found the cause of one type to be genetic mutations involving one or more genes. The excess red blood cells increase the risk for blood clots which could prevent blood flow to major organs such as the heart, lungs, or brain. ErythrocytosisĮrythrocytosis is a rare inherited blood disorder where the body produces too many red blood cells. Bone marrow transplants are often used to treat the disease, especially in children. Treatment for thalassemia often involves regular blood transfusions and folate supplements. A blood test is used to diagnose thalassemia and during a physical exam, the doctor will often look for an enlarged spleen, which is often a symptom. Thalassemia is an inherited blood disorder in which the body makes an abnormal form of hemoglobin which results in large numbers of red blood cells being destroyed, which leads to anemia. The lack of blood flow can cause pain, infection, and problems with organs not receiving the adequate amount of blood. In people with sickle cell, their red blood cells are shaped like a half moon (or a sickle), so they have difficulty flowing into the small blood vessels and often get blocked. Healthy blood cells are fluid in shape so they can easily pass through the small blood vessels in the body. Sickle cell anemia is the most common type of inherited blood disorders. Talk with your healthcare provider if you think you are at risk for anemia or experienced any of the listed symptoms. Treatment for anemia varies according to the type of anemia. ![]() Inflammatory bowel disease (Crohn disease or ulcerative colitis).Rheumatoid arthritis or other autoimmune disorders.People with one or more of the following chronic conditions are also at a greater risk for developing anemia: People who run or engage in other strenuous sports or activities have a greater chance for developing anemia due to their blood cells breaking down. The risk of anemia increases with age and with activity. When a problem with red blood cell production or function occurs, the body does not get the oxygen that it needs which could cause one or more of the following symptoms.Ĭhronic disease, infections, poor diet, and intestinal disorders are all common causes of anemia. Anemia:Īnemia occurs when your body is not producing enough red blood cells or when the red blood cells are not properly functioning. While there are many different types, below are some of the more commonly seen red blood cell disorders.
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